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Practice Locations

CU Medicine Medical Oncology
Highlands Ranch Specialty Care Center
1500 Park Central Drive Suite 101, Highlands Ranch, CO 80129

720-516-1100

Wells Messersmith, MD

Physician

Board Certified

Schedule Appointment

Wells Messersmith, MD

Physician

Board Certified

GENDER

Male

LANGUAGE

English

DEPARTMENT

Medicine

Specialty

Internal Medicine, Medical Oncology

Primary Clinic Phone

(720) 848-0300

Locations

Practice Locations

UCH - Cancer Center
1665 Aurora Ct Aurora, CO 80045

720-848-0300

CU Medicine Medical Oncology
Highlands Ranch Specialty Care Center
1500 Park Central Drive Suite 101, Highlands Ranch, CO 80129

720-516-1100

UCH - Anschutz Outpatient Pavilion
1635 Aurora Ct Aurora, CO 80045

720-848-0000

UCHealth - Lone Tree Health Center
9548 Park Meadows Drive Lone Tree, CO 80124

720-848-2200

University of Colorado Hospital (UCH)
12605 E. 16th Ave Aurora, CO 80045

720-848-0000

Clinical Interest for Patients

I am interested in Gastrointestinal Cancers (Colorectal, Pancreatic, Gastric, Esophageal, Hepatocellular, Gallbladder, Bile Ducts, Anal, GI, Stromal Tumors, Abdominal Carcinoma of Unknown Primary), Drug Development (Experimental Therapeutics) and Translational Research.


Care Philosophy

We strive to provide patient-focused, personalized, multi-disciplinary care for gastrointestinal (GI) cancers. Our specialized providers in Medical Oncology (chemotherapy and targeted therapies), Surgical Oncology, Radiation Oncology, Pathology, Molecular Pathology, Radiology, Interventional Radiology, Nuclear Medicine, Gastroenterology (both Hepatology and Interventional Endoscopy), Nutrition, and Integrative Medicine work together to achieve the best outcomes for our patients. We have weekly GI cancer tumor boards, where our specialists come together to discuss patients and patient care.


Specialties

  • Internal Medicine ( 2001 )
  • Medical Oncology ( 2003 )

Conditions & Treatments

  • Cancers

    Anal Cancer, Colorectal Cancer, Gastroenterologic Cancer (Colon, Stomach, Esophageal, Liver), Pancreatic Cancer

  • Digestive System

    Gastroenterology (Stomach, Bowel, General GI Problems)

Volunteer Activities

I have given GI cancer lectures at national meetings (ASCO, AACR) and at community cancer centers across the US and Europe. I also participate in grant, abstract, and manuscript reviews in my field.


Medical Schools

MD, Harvard Medical School (1998)


Undergraduate Schools

BA, Williams College (MA) (1992)


Internships

Massachusetts General Hospital Program


Residency Program

Massachusetts General Hospital Program (2001)


Fellowships

Johns Hopkins University School of Medicine Program (2004)

AACR - American Association of Cancer Research, Member


ASCO - American Association of Clinical Oncology, Member


Research Interests for Patients

My lab is mainly focused on using a personalized approach in developing new anticancer drugs for GI cancers. In particular, the lab uses a novel colorectal and pancreatic explant model whereby tumor tissue is obtained from the operating room and then placed directly into mice. Tumors are treated with new drugs and predictive biomarkers of sensitivity are discovered. These predictive markers are used in the clinic to pre-select patients that would most likely derive benefit from these new drugs. Additionally, these tumors are evaluated in orthotopic and metastatic models. Current anticancer drugs in the lab target Notch (g-secretase), Src, and hedgehog pathways.

information for referring providers

Clinical Interests for Referring Providers

Gastrointestinal Cancers (Colorectal, Pancreatic, Gastric, Esophageal, Hepatocellular, Gallbladder, Bile Ducts, Anal, GI, Stromal Tumors, Abdominal Carcinoma of Unknown Primary), Drug Development (Experimental Therapeutics), Translational Research

Research Interest for Referring Providers

My lab is mainly focused on using a personalized approach in developing new anticancer drugs for GI cancers. In particular, the lab uses a novel colorectal and pancreatic explant model whereby tumor tissue is obtained from the operating room and then placed directly into mice. Tumors are treated with new drugs and predictive biomarkers of sensitivity are discovered. These predictive markers are used in the clinic to pre-select patients that would most likely derive benefit from these new drugs. Additionally, these tumors are evaluated in orthotopic and metastatic models. Current anticancer drugs in the lab target Notch (g-secretase), Src, and hedgehog pathways.


Referral Contact Phone: 720-848-0300

Referral Contact Fax: 720-848-0360