University of Colorado Cancer Center
CU Anschutz Medical Campus1665 Aurora Ct Aurora, CO 80045
CU Medicine Medical Oncology
Highlands Ranch Specialty Care Center1500 Park Central Drive Suite 101, Highlands Ranch, CO 80129
UCHealth Anschutz Outpatient Pavilion - Anschutz Medical Campus1635 Aurora Ct Aurora, CO 80045
UCHealth Lone Tree Medical Center9548 Park Meadows Drive Lone Tree, CO 80124
UCHealth University of Colorado Hospital (UCH)12605 E. 16th Ave Aurora, CO 80045
Clinical Interest for Patients
I am interested in Gastrointestinal Cancers (Colorectal, Pancreatic, Gastric, Esophageal, Hepatocellular, Gallbladder, Bile Ducts, Anal, GI, Stromal Tumors, Abdominal Carcinoma of Unknown Primary), Drug Development (Experimental Therapeutics) and Translational Research.
We strive to provide patient-focused, personalized, multi-disciplinary care for gastrointestinal (GI) cancers. Our specialized providers in Medical Oncology (chemotherapy and targeted therapies), Surgical Oncology, Radiation Oncology, Pathology, Molecular Pathology, Radiology, Interventional Radiology, Nuclear Medicine, Gastroenterology (both Hepatology and Interventional Endoscopy), Nutrition, and Integrative Medicine work together to achieve the best outcomes for our patients. We have weekly GI cancer tumor boards, where our specialists come together to discuss patients and patient care.
- Internal Medicine ( 2001 )
- Medical Oncology ( 2003 )
Conditions & Treatments
Anal Cancer, Colorectal Cancer, Gastroenterologic Cancer (Colon, Stomach, Esophageal, Liver), Pancreatic Cancer
Gastroenterology (Stomach, Bowel, General GI Problems)
Interests & Activities
I have given GI cancer lectures at national meetings (ASCO, AACR) and at community cancer centers across the US and Europe. I also participate in grant, abstract, and manuscript reviews in my field.
Education & Training
MD, Harvard Medical School (1998)
BA, Williams College (MA) (1992)
Massachusetts General Hospital Program (1999)
Massachusetts General Hospital Program (2001)
Johns Hopkins University School of Medicine Program (2004)
AACR - American Association of Cancer Research, Member
ASCO - American Association of Clinical Oncology, Member
Research & Grants
Research Interests for Patients
My lab is mainly focused on using a personalized approach in developing new anticancer drugs for GI cancers. In particular, the lab uses a novel colorectal and pancreatic explant model whereby tumor tissue is obtained from the operating room and then placed directly into mice. Tumors are treated with new drugs and predictive biomarkers of sensitivity are discovered. These predictive markers are used in the clinic to pre-select patients that would most likely derive benefit from these new drugs. Additionally, these tumors are evaluated in orthotopic and metastatic models. Current anticancer drugs in the lab target Notch (g-secretase), Src, and hedgehog pathways.