Joseph Hippensteel, MD
Pulmonary Disease and Critical Care Medicine
Locations
Practice Locations
UCHealth University of Colorado Hospital (UCH)
720-848-0000
Provider Expertise
Clinical Interest for Patients
Critical Illness Survivorship, Detection and Treatment of Delirium in Critically Ill Patients
Specialties
- Pulmonary Disease and Critical Care Medicine ( 2018 )
Education & Training
Medical Schools
MD, University of Wisconsin School of Medicine and Public Health (2012)
Undergraduate Schools
BS, University of Wisconsin–Madison (WI) (2007)
Graduate Schools
MS, University of Wisconsin - Madison (2008)
Internships
University of California (San Francisco) Program (2013)
Residency Program
University of California (San Francisco) Program (2015)
Fellowships
University of Colorado (2019)
Research & Grants
Grants
Potentiation of a-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors (AMPAR) by highly-sulfated chondroitin sulfate: a novel contributor to sepsis-associated delirium (2020)
Potentiation of (AMPAR) by highly-sulfated chondroitin sulfate: a novel contributor to sepsis-associated delirium. (2020)
Development of a Pre-Clinical Murine Model of Sepsis-associated Delirium (2021)
Endothelial Glycocalyx Degradation during Sepsis in Aging (2021)
Lung-Brain Axis as a Mediator of Delirium (2021)
Mass Spectrometry Imaging of Glycosaminoglycans in Biological Samples (2023)
Understanding Sepsis-associated Auditory Dysfunction (2025)
Research Interests for Patients
My research interests focus on the cognitive consequences (i.e., acutely as delirium and chronically as long-term cognitive dysfunction) of sepsis and other critical illness. I perform both basic and translational research in this realm seeking to identify the relevance of brain-penetrating heparan sulfate and chondroitin sulfate in these conditions. Ultimately, I seek to develop novel biomarkers and/or therapeutics for these understudied problems.